Cortexyme to Present New GAIN Trial Data at AD/PD 2022

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New facts expands evidence foundation of part of P. gingivalis in Alzheimer’s sickness

Dialogue to contain new biomarker success and correlations in between biomarkers and scientific outcomes

SOUTH SAN FRANCISCO, Calif., March 14, 2022–(Enterprise WIRE)–Cortexyme, Inc. (Nasdaq: CRTX), a scientific-phase biopharmaceutical company groundbreaking upstream therapeutic approaches to boost the life of clients identified with degenerative ailments, declared that the corporation will participate at the Ad/PD™ 2022 Intercontinental Meeting on Alzheimer’s and Parkinson’s Ailments, which is a hybrid function taking area March 15-20, 2022 in Barcelona, Spain, as properly as pretty much. Cortexyme’s chief health care officer Michael Detke, MD, PhD, will current new Obtain Demo effects and biomarker data examining the purpose of P. gingivalis in Alzheimer’s condition and the P. gingivalis-beneficial population, in addition to sharing analyze knowledge that reinforces the efficacy of the company’s initially-in-class gingipain inhibitor in slowing cognitive decline in Alzheimer’s disorder with P. gingivalis. These new info analyses will be reviewed at Advertisement/PD 2022 and at additional conferences as additional data gets to be obtainable all over 2022.

Advert/PD 2022 Summary Facts

Title: Facts from the Period 2/3 Attain Demo of COR388 (Atuzaginstat) for the Remedy of Mild-Average Alzheimer’s Ailment

  • Presenter: Michael Detke, MD, PhD, Cortexyme’s chief healthcare officer.

  • Authors: Michael Detke1, Marwan Sabbagh2, Mark Ryder3, Joanna Bolger1, Dave Hennings1, Vladimir Skljarevski1, Shirin Kapur1, Debasish Raha1, Florian Ermini1, Mai Nguyen1, Ursula Haditsch1, Kim Perry4, Kelly Ritch5, Suzanne Hendrix6, Sam Dickson6, Hatice Hasturk7, Sarah Horine1, Craig Mallinckrodt1, Leslie Holsinger1, Casey Lynch1, and Stephen Dominy1.

  • Accessibility: Cortexyme’s Advertisement/PD 2022 presentation will choose put on Sunday, March 20, 2022, at 10:50 a.m. CET (5:50 a.m. EDT) and will be accessible to Advertisement/PD 2022 registered conference attendees in-individual and on its digital platform. The company will difficulty a news launch summarizing highlights of the presentation and write-up the presentation to the science portion of its corporate web page soon immediately after the conclusion of the presentation.

1Cortexyme – South San Francisco, CA (United states), 2Barrow Neurological Institute, Dignity Well being/St. Joseph’s Hospital and Health-related Middle – Phoenix, AZ (United states), 3UCSF – San Francisco, CA (Usa), 4Innovative Analytics – Portage, MI (United states), 5Datafy Scientific R&D – Portage, MI (United states of america), 6Pentara Corporation – Millcreek, UT (United states), 7Forsyth Institute – Cambridge, MA (Usa)

About Cortexyme

Cortexyme, Inc. (Nasdaq: CRTX) is a medical stage biopharmaceutical business revolutionary upstream therapeutic techniques built to strengthen the lives of patients diagnosed with degenerative health conditions, which include Alzheimer’s disorder, periodontitis, and oral perhaps malignant disorders, among the others. Cortexyme’s ground breaking solution targets a unique, infectious pathogen termed P. gingivalis discovered in the brain of Alzheimer’s patients and other organs and tied to degeneration and swelling in human beings and animal versions. The company’s causation evidence for Alzheimer’s condition and the mechanism of its novel therapeutic has been independently replicated and confirmed by a number of laboratories all around the entire world, as well as released in peer-reviewed scientific journals. To discover extra about Cortexyme, stop by www.cortexyme.com or observe @Cortexyme on Twitter.

Ahead-Wanting Statements

Statements in this news release comprise “forward-wanting statements” that are issue to substantial challenges and uncertainties. Ahead-wanting statements contained in this news release may well be recognized by the use of terms such as “results,” “intends,” “will,” “estimate,” “potential,” “correlations,” “reinforces” or other identical text. Examples of ahead-on the lookout statements involve, among the others, the strategic improvement route for atuzaginstat its company ideas, internal and external improvement of the pipeline, approach, prepared Food and drug administration submissions and clinical trials and timeline, prospective customers, and milestone anticipations the timing and good results of the company’s scientific trials and linked data, which includes designs and the capability to initiate, carry out and/or full latest and added research the timing of bulletins and updates relating to its scientific trials and connected facts the potential therapeutic gains, safety and efficacy of the company’s item candidate or library of compounds and statements about its potential to acquire, and the timing relating to, more development of atuzaginstat and other plans or indications, regulatory submissions and interactions with regulators, and relevant response and decisions, and approvals with respect to the company’s drug product or service candidate. Forward-on the lookout statements are dependent on Cortexyme’s existing anticipations and are subject matter to inherent uncertainties, pitfalls, and assumptions that are tricky to forecast and could result in real final results to vary materially from what the business expects. More, sure ahead-seeking statements are based mostly on assumptions as to potential occasions that may not confirm to be correct. Variables that could cause genuine outcomes to differ include things like, but are not restricted to, the threats and uncertainties described in the part titled “Risk Components” in Cortexyme’s Yearly Report on Form 10-K filed with the Securities and Exchange Commission (SEC) on March 1, 2022, its Quarterly Report on Sort 10-Q submitted with the SEC on October 29, 2021, and other reviews as filed with the SEC. Ahead-wanting statements contained in this information launch are built as of this date, and Cortexyme undertakes no obligation to update this sort of info other than as demanded below applicable law.

Look at source version on businesswire.com: https://www.businesswire.com/information/house/20220314005261/en/

Contacts

Stacy Roughan
Cortexyme, Inc.
Vice President, Corporate Communications & Trader Relations
[email protected]

By Lois C